Complementary Insulin Combinations to Optimize Glycemic Control in T2D

Program Medium

Internet-based program


Estimated Time to Complete Educational Activity

2.5 hours


Course Overview

In this web-based program, physicians and optometrists will learn how recent developments have helped to advance the management of Type 2 diabetes.

Release Date: July 14, 2017

Expiration Date: July 14, 2019


Method of Physician Participation Utilized in Learning Process

There are no fees for participating and receiving CME credit for this activity. During the period January 6, 2017  through January 6, 2019 participants must:
1) read the learning objectives and faculty disclosures;
2) study the educational activity, and are expected to view all 9 segments totaling 1.5 hours to successfully complete the activity and earn CME credit;
3) register and complete the evaluation form and post-test;
4) score 100% on the post-test; and
5) print out your CME certificate.



Participation in this WebCAST is complimentary, and clinicians are invited to view this CME-certified program and/or share this invitation with other colleagues, departmental staff members, and healthcare professionals.


Grantor Support

Supported by an educational grant from Sanofi Diabetes.


Accreditation Statement

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the University of Massachusetts Medical School and CMEducation Resources, LLC. ‘The University of Massachusetts Medical School is accredited by the ACCME to provide continuing medical education for physician.


Credit Designation Statement

Postgraduate Institute for Medicine designates this enduring activity for a maximum of 2.5 AMA PRA Category 1 Credits™.Physicians should claim only the credit commensurate with the extent of their participation in the activity.


Policy on Faculty & Provider Disclosure

Postgraduate Institute for Medicine (PIM) requires instructors, planners, managers and other individuals who are in a position to control the content of this activity to disclose any real or apparent conflict of interest (COI) they may have as related to the content of this activity. All identified COI are thoroughly vetted and resolved according to PIM policy.  The existence or absence of COI for everyone in a position to control content will be disclosed to participants prior to the start of each activity.


Other Credits

American Nurses Credentialing Center (ANCC) accepts AMA PRA Category 1 Credits™ from organizations accredited by the ACCME.
American Academy of Nurse Practitioners (AANP) accepts AMA PRA Category 1 Credits™ from organizations accredited by the ACCME.
American Academy of Physician Assistants (AAPA) accepts certificates of participation for educational activities certified for AMA PRA Category 1 Credits™ from organizations accredited by the ACCM.


Program Faculty and Disclosure

Program Chair

Professor of Medicine and Pharmacology
Tulis Tulane Alumni Chair in Diabetes
Chief, Section of Endocrinology
Tulane University Health Sciences Center
New Orleans, LA
Research Support (To Tulane): Grants from Asahi, Bayer
Consulting and Speaking: Takeda, Novo Nordisk, Sanofi-aventis, Eli Lilly, Astra-Zeneca, Janssen

Clinical Assistant Professor of Medicine
University of California
National Research Institute
Los, Angeles, California
Consulting: Astra Zeneca, BMS, Johnson and Johnson, Novo Nordisk, Sanofi
Speaker’s Bureau: Sanofi, Eli Lilly, Novo Nordisk, Astra Zeneca
Contracted Research: AbbVie, AstraZeneca, Boehringer Ingelheim, BMS, Elcelyx, Eli Lilly, IONIS, Janssen, Johnson and Johnson, Ligand, Merck, Mylan, Novartis, Novo Nordisk, Pfizer, Sanofi, Theracos, vTv

Director, Ochsner Diabetes Clinical Research Unit,
Frank Riddick Diabetes Institute,
Department of Endocrinology, 
Ochsner Medical Center
New Orleans, LA
Grant/Research Support: AstraZeneca, Janssen Pharmaceuticals, Inc., Lexicon Pharmaceuticals, Inc., Merck & Co.
Speaker Honoraria: Novo Nordisk, Sanofi, AstraZeneca, Janssen Pharmaceuticals, Inc.,
Consultant: Merck & Co., Novo Nordisk, Sanofi, AstraZeneca, GlaxoSmithKline, Intarcia Therapeutics, Inc., Janssen Pharmaceuticals, Inc., Merck & Co., Inc., Novo Nordisk, Sanofi

Associate Professor of Medicine
Georgetown University School of Medicine
Physician Investigator, Scientific Director 
MedStar Health Research Institute
Hyattsville, MD

Consultant and Grant/Research Support: Novo Nordisk, Sanofi


Educational Objectives

Upon completion of this activity, participants will be able to: 

  • Identify patients who, because of postprandial hyperglycemia, are not optimizing overall HA1c target goal attainment; and who, therefore, may be appropriate candidates for therapy with specific agents, including GLP-1 agonists, in combination with basal insulin, to optimize their glycemic management
  • Apply titration strategies for the dose(s) of both basal insulin and a GLP-1 agonist, when used in combination formulations, to achieve optimal HA1c control, weight loss, reduction in risk of hypoglycemia, and postprandial glucose control
  • Describe the mechanisms, metabolic issues, and physiological rationale for combining anti-hyperglycemic agents—such as basal insulin, that preferentially targets fasting hyperglycemia, in conjunction with agents such as GLP-1 agonists that preferentially target postprandial hyperglycemia—in order to optimize glycemic management and HA1c targets in patients with T2D
  • Identify T2D patients in whom the possible advantages of incretin system-targeted therapy with GLP-1 agonists—including better PPG control, weight loss, and HA1c reductions— may make them guideline-appropriate candidates for combination regimens
  • Individualize multimodal, pharmacologic management in patients with T2D, and improve patient outcomes by deploying combination regimens that act through multiple, complementary mechanisms—including new basal insulin and incretin system-targeted combination-based interventions—to achieve ADA/EASD target goals


Hardware and Software Requirements:

To participate in this program, viewers must have a PC or Macintosh computer that has active, ongoing internet access for the duration of the program, as well as a compatible Flash-viewer. An email address is required for registration, and a printer is required to print out the CME certificate.


Privacy Policy

When you participate in a CME activity offered by CMEducation Resources, we ask you for your name, degree, affiliation, street address, telephone number, fax number, and/or e-mail address (the "Information"). We use that Information in the following ways:

• We use the Information to grade your post-test and to send you a certificate of completion of the CME activity. If we use a third-party company to grade your post-test and issue certificates of completion, we will give the Information to that company for that purpose only.

• For each CME activity that you take, you must complete an evaluation questionnaire. That questionnaire asks if you are willing to participate in a follow-up survey. If you answer yes, we will use your name and contact information to send you the survey.

• We may use the Information to send you information about other CME activities that CMEducation Resources is offering.

• If our company is acquired by or merged into another company, we may make the Information available to the new owner/entity to use in the ways described above, to enable it to continue our business.

• You should check this privacy policy periodically to see whether we have made any changes