New Frontiers and Technological Advances in Noninvasive Prenatal Screening
The Changing Paradigm for Prenatal Screening for Fetal Aneuploidy:
Technologies Used in Counting versus SNP-based NIPS, Overall Performance of NIPS, Sensitivity Specificity and PPV Microdeletion Detection, and Microdeletions Performance for SNP-based NIPSThe Role of SNP-Based Diagnostic Tests for Detecting the Full Range of Fetal Abnormalities
Including Critical Microdeletions and Aneuplodies: What Do the Clinical Studies Teach Us? How Do They Guide Us at the Front Lines of OB-GYN and MFM Care? Peter Benn, PhD – Program ChairProgram Medium
Internet-based program
Estimated Time to Complete Educational Activity
1.5 hours
Course Overview
In this web-based program, physicians will learn how ecent developments in noninvasive prenatal screening have helped to advance the detection of fetal genetic abnormalities.
Release Date
June 6, 2017
Expiration Date
June 6, 2019
Method of Physician Participation Utilized in Learning Process
There are no fees for participating and receiving CME credit for this activity. During the period June 6, 2017 through June 6, 2019 participants must 1) read the learning objectives and faculty disclosures; 2) study the educational activity, and are expected to view all 7 segments totaling 2.5 hours to successfully complete the activity and earn CME credit; 3) register and complete the evaluation form and post-test; 4) score 100% on the post-test; and 5) print out your CME certificate.
Registration
Participation in this WebCAST is complimentary, and clinicians are invited to view this CME-certified program and/or share this invitation with other colleagues, departmental staff members, and healthcare professionals..
Grantor Support
Supported by an educational grant from Natera.
Accreditation Statement
This activity has been planned and implemented in accordance with accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the University of Massachusetts Medical School and CMEducation Resources, LLC. University of Massachusetts Medical School is accredited by the ACCME to provide continuing medical education for physicians.
Credit Designation Statement
The University of Massachusetts Medical School designates this enduring material for a maximum of 1.5 AMA PRA Category 1 Credits(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Policy on Faculty & Provider Disclosure
It is the policy of the University of Massachusetts Medical School to ensure fair balance, independence, objectivity and scientific rigor in all activities. All faculty participating in CME activities sponsored by the University of Massachusetts Medical School are required to present evidence-based data, identify and reference off-label product use and disclose all relevant financial relationships with those supporting the activity or others whose products or services are discussed. Faculty disclosure will be provided in the activity materials.
Other Credits
American Nurses Credentialing Center (ANCC) accepts AMA PRA Category 1 Credits™ from organizations accredited by the ACCME.
American Academy of Nurse Practitioners (AANP) accepts AMA PRA Category 1 Credits™ from organizations accredited by the ACCME.
American Academy of Physician Assistants (AAPA) accepts certificates of participation for educational activities certified for AMA PRA Category 1 Credits™ from organizations accredited by the ACCM.
Program Faculty and Disclosure
PETER BENN, PhD
Program Chair
Professor Emeritus
Department of Genetics and Genome Sciences
Director, Human Genetics Laboratory
University of Connecticut Health Center
Farmington, CT
Consultant: Natera
Stock Options: Natera
ERROL R. NORWITZ, MD, PhD, MBA
Louis E. Phaneuf Professor, Departments of Obstetrics & Gynecology
Tufts University School of Medicine
Chairman, Department of Obstetrics & Gynecology
Tufts Medical Center
Boston, MA
Consultant: Natera
MIKE RUMA, MD, MPH, FACOG
Perinatal Associates of New Mexico
Albuquerque, NM
Consultant: Natera
Educational Objectives
Upon completion of this activity, participants will be able to:
- Outline the evolution of prenatal diagnosis and screening for chromosome abnormalities such as Down syndrome;
- Apply non-invasive prenatal screening (NIPT) using cell-free fetal DNA, and understand how it integrates into the current paradigms for screening and diagnostic testing for aneuploidy;
- Compare the different laboratory techniques used to amplify cell-free DNA; and how the two methods, generally described as the “counting method” and the “SNP (single nucleotide polymorphism)based testing” differ in their clinical application, limitations, and potential advantages;
- Detail the SNP based approach to NIPT, and outline the advantages this technology offers compared to the “counting method”; and, specifically, how the different methodologies—i.e. the counting method versus that focused on SNP technology—impact the reliability, predictive value, and usefulness of the NIPT results;
- Apply current practice guidelines from various professional societies such as ACOG and SMFM regarding the integration of NIPT into clinical practice; including, a clinical roadmap for how, on a practical level, clinicians should utilize NIPT in their practice
Hardware and Software Requirements:
To participate in this program, viewers must have a PC or Macintosh computer that has active, ongoing internet access for the duration of the program, as well as a compatible Flash-viewer. An email address is required for registration, and a printer is required to print out the CME certificate.
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Copyright © 2017 by CMEducation Resources, LLC All rights reserved.
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Content on this webcast reflects the opinions, output, and analyses of experts, investigators, educators, and clinicians whose activities for, while independent, are commercially supported by the sponsor noted at the start of each activity.
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